RESOURCE OVERVIEW

Vial fogging is a common phenomenon observed in lyophilized biologic drug products, characterized by a haze of dried powder forming above the cake's surface inside the vial. This haze can appear as a dendritic pattern, branching, or a uniform fog. While often considered a cosmetic defect, severe fogging can lead to the costly rejection of entire product batches.

In this whitepaper learn more from the Simtra BioPharma Solutions team about vial selection and vial fogging. Simtra’s R&D team in Bloomington, Indiana, home of the Lyophilization Center of Excellence, is uniquely positioned to support vial fogging studies as either standalone vial selection studies or as a part of larger formulation and lyophilization cycle development studies.

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